Potential Adverse Effects of Amphetamine Treatment on Brain and Behavior: A Review PMC

what are the effects of amphetamines

Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Amphetamine is also used for weight reduction in patients with obesity. Treatment programs use behavior change techniques through counseling (talk therapy). The goal is to help you understand your behaviors and why you use amphetamines. Involving family and friends during counseling can help support you and keep you from going back to using (relapsing).

  • Recent reports have added some clarity to the issue, and the NIH National Toxicology Program concluded that there was concern for neurobehavioral developmental toxicity from amphetamines 23.
  • Amphetamines have been used since then in the development of a variety of drugs, most notably Adderall and Ritalin, which treat ADD and ADHD.
  • Despite this legislation, and medical recommendations to limit amphetamine use, some physicians continued to write off-label prescriptions, often with insufficient follow-up monitoring, and abuse continued to grow.
  • Among people who use meth/amphetamines, ‘ice’ is the most used form (50% of people who use meth/amphetamine use ‘ice’).
  • Due to concerns over their side effects, however, amphetamines are increasingly being replaced by modafinil, a medication that promotes wakefulness.

Can You Overdose on Amphetamines?

what are the effects of amphetamines

While not common, serious side effects have been reported with Adderall. Certain people may be at higher risk of these side effects based on other medical conditions they may have. In early 2018, The New York Times reported that methamphetamine use in the U.S. had greatly increased over the past decade. In Portland, Oregon, more than 200 people died from methamphetamine use in 2016; that was three times more than just 10 years earlier, the Times reported. Portland was just one such example of a location that inundated by methamphetamine use.

International Patients

When taken properly, amphetamine-based medications can be safe and effective. But as with any prescribed medication, there are potential side effects. Morgan is a mental health counselor who works alongside individuals of all backgrounds struggling with eating disorders. Morgan is freelance mental health and creative writer who regularly contributes to publications including, Psychology Today.

Amphetamine dependence, tolerance and withdrawal

what are the effects of amphetamines

Use with medications that increase stomach or urine alkalinity, including sodium bicarbonate, acetazolamide, and some thiazide diuretics (water pill) should be avoided. Do not use this medicine if you are using or have used an MAO inhibitor (MAOI), including isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]), within the past 14 days. Ask your healthcare professional how you should dispose of any medicine you do not use.

Attention deficit hyperactivity disorder

Check with your doctor right away if you or your child have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Uses and risks of amphetamine

While the physical changes amphetamines cause in the brain are permanent, several therapeutic treatment programs that can help people overcome their addiction. The most-successful treatments include addiction education, family counseling, cognitive behavior therapy and peer-support groups. Amphetamines also cause an increase in norepinephrine, the hormone involved how long do amphetamines stay in your system with the activation of the sympathetic nervous system, which is what controls our “fight-or-flight” mechanism, Franssen said. Norepinephrine causes the physical side effects, such as increased respiration, heart rate and blood pressure. Additional clinical trials found that amphetamine had positive effects on weight loss, narcolepsy and depression.

  • Tell your doctor right away if you or your family notice any unusual changes in behavior, including an increase in aggression, hostility, agitation, irritability, or suicidal thinking or behavior.
  • A safe and effective dose hasn’t been established for this age group.
  • During your Adderall treatment, consider taking notes on any side effects you’re having.
  • Your doctor may check your blood pressure and heart rate regularly during treatment with this drug.
  • Amphetamines remain among the most effective appetite suppressants.

Adderall Interactions and Long-Term Effects

what are the effects of amphetamines

Meth is smoked, snorted, injected, and can reach the brain quickly, causing considerable damage. Some are common, and others are more serious, especially with misuse or use in combination with other substances like alcohol, opioids, or other stimulants. Always take your amphetamines on a schedule or at the same time each day to avoid experiencing withdrawal symptoms.

Effects on Growth

Your child’s doctor may monitor your child’s height and weight during treatment with this drug. The oral tablet isn’t recommended for children under 3 years of age. It isn’t fully understood how it works for narcolepsy, ADHD, or weight loss.

  • The different salts and beads are metabolized at different rates, resulting in a less dramatic onset and termination of therapeutic action.
  • Taking amphetamine during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby.
  • There is evidence that amphetamine use to treat ADHD could slow growth in children.
  • Here we look at the types of amphetamines, their effects, potential for addiction, and treatment options.
  • Misusing Adderall can cause serious side effects or overdose, which can be life threatening or fatal.

What are the more common side effects of Adderall?

what are the effects of amphetamines

Identifying addiction isn’t always easy and it’s best to leave diagnosis to healthcare professionals. However, it can be helpful to know the diagnostic criteria if you think that you or someone you care about has an addiction to amphetamines. Taking amphetamine during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Amphetamine is used to treat attention deficit hyperactivity disorder (ADHD). The estimated annual prevalence of a stimulant use disorder involving amphetamines is 0.2 percent among U.S. adults, according to the DSM-5.

  • Adderall can sometimes cause harmful effects in people who have certain conditions.
  • Both amphetamine and methamphetamine are stimulant drugs that have different effects on your body based on the chemicals that make up each drug.
  • Adderall may cause mild side effects other than those listed above.
  • Always follow your healthcare provider’s instructions when taking amphetamines.

Amphetamines increase dopamine and serotonin levels – the feel-good chemicals in the brain. As with similar stimulants, methamphetamine is most often used in a “binge and crash” pattern. Because the pleasurable effects disappear even before the drug concentration in the blood falls significantly, users try to maintain the high by bingeing on the drug. In some cases, abusers indulge in a form of bingeing known as a “run,” forgoing food and sleep while continuing abuse for up to several days. If you experience withdrawal symptoms while you’re following your prescribed schedule, talk with your healthcare provider.

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