Grants JM, Ying LT, Yoda A, You CC, Okano H, Sawa H, Taubert S. The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegans. Genetics. 2015 Dec 29. pii: genetics.115.180265. [Epub ahead of print] PMID:26715664【PubMed】
Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, Nakamura M, Okano H. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. 2015 Dec 16. pii: S2213-6711(15)00349-5. doi: 10.1016/j.stemcr.2015.11.013. [Epub ahead of print]PMID:26724902[PubMed]
Hasegawa M, Hara-Miyauchi C, Ohta H, Sakimura K, Okano H, Okano HJ. Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS. Neurosci Res. 2015 Dec 7. pii: S0168-0102(15)00289-8. doi: 10.1016/j.neures.2015.11.009. [Epub ahead of print][PubMed]
Kobayashi R, Takahashi-Fujigasaki J, Shiozawa S, Hara-Miyauchi C, Inoue T, Okano HJ, Sasaki E, Okano H. α-synuclein aggregation in the olfactory bulb of middle-aged common marmoset. Neurosci Res. 2015 Nov 28. pii: S0168-0102(15)00286-2. doi: 10.1016/j.neures.2015.11.006. [Epub ahead of print][PubMed]
Shimojo D, Onodera K, Doi-Torii Y, Ishihara Y, Hattori C, Miwa Y, Tanaka S, Okada R, Ohyama M, Shoji M, Nakanishi A, Doyu M, Okano H, Okada Y.Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells. Mol Brain. 2015 Dec 1;8(1):79. doi: 10.1186/s13041-015-0172-4.[PubMed]
Yamada I, Hikishima K, Miyasaka N, Kato K, Kojima K, Kawano T, Ito E, Kobayashi D, Eishi Y, Okano H. Gastric carcinoma: evaluation with diffusion-tensor MR imaging and tractography ex vivo. Magn Reson Imaging. 2015 Oct 24. pii: S0730-725X(15)00244-1. doi: 10.1016/j.mri.2015.10.007. [Epub ahead of print] [PubMed]
Sato K, Kuroki Y, Kumita W, Fujiyama A, Toyoda A, Kawai J, Iriki A, Sasaki E, Okano H, Sakakibara Y. Resequencing of the common marmoset genome improves genome assemblies and gene-coding sequence analysis. Sci Rep. 2015 Nov 20;5:16894. doi: 10.1038/srep16894. [PubMed]
Imaizumi K, Sone T, Ibata K, Fujimori K, Yuzaki M, Akamatsu W, Okano H.
Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes. Stem Cell Reports. 2015 Nov 4. pii: S2213-6711(15)00302-1. doi: 10.1016/j.stemcr.2015.10.005. [Epub ahead of print] [PubMed]
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T.Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism. Sci Rep. 2015 Nov 9;5:16239. doi: 10.1038/srep16239.
[PubMed]
Lin ZY, Hikabe O, Suzuki S, Hirano T, Siomi H, Sasaki E, Imamura M, Okano H. Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey. Primates. 2015 Nov 3. [Epub ahead of print] [PubMed]
Yasui T, Mabuchi Y, Toriumi H, Ebine T, Niibe K, Houlihan DD, Morikawa S, Onizawa K, Kawana H, Akazawa C, Suzuki N, Nakagawa T, Okano H, Matsuzaki Y. Purified Human Dental Pulp Stem Cells Promote Osteogenic Regeneration. J Dent Res. 2015 Oct 22. pii: 0022034515610748. [Epub ahead of print] [PubMed]
Nakata M, Yamamoto S, Okada T, Darambazar G, Okano H, Ozawa K, Yada T. IL-10 gene transfer upregulates arcuate POMC and ameliorates hyperphagia, obesity and diabetes by substituting for leptin. Int J Obes (Lond). 2015 Oct 5. doi: 10.1038/ijo.2015.201. [Epub ahead of print] [PubMed]
Kanzaki S, Watanabe K, Fujioka M, Shibata S, Nakamura M, Okano HJ, Okano H, Ogawa K. Novel in vivo imaging analysis of an inner ear drug delivery system: drug availability in inner ear following different dose of systemic drug injections. Hear Res. 2015 Oct 1. pii: S0378-5955(15)00199-9. doi: 10.1016/j.heares.2015.09.018. [Epub ahead of print] [PubMed]
Kohro Y, Sakaguchi E, Tashima R, Tozaki-Saitoh H, Okano H, Inoue K, Tsuda M. A new minimally-invasive method for microinjection into the mouse spinal dorsal horn. Sci Rep. 2015 Sep 21;5:14306. doi: 10.1038/srep14306. [PubMed]
Yamada I, Hikishima K, Miyasaka N, Kato K, Ito E, Kojima K, Kawano T, Kobayashi D, Eishi Y, Okano H. q-space MR imaging of gastric carcinoma ex vivo: Correlation with histopathologic findings. Magn Reson Med. 2015 Aug 29. doi: 10.1002/mrm.25905. [Epub ahead of print] [PubMed]
Ohtsuka T, Yano M, Okano H. Acute reduction of neuronal RNA binding Elavl2 protein and Gap43 mRNA in mouse hippocampus after kainic acid treatment. Biochem Biophys Res Commun. 2015 Aug 30. pii: S0006-291X(15)30495-2. doi: 10.1016/j.bbrc.2015.08.103. [Epub ahead of print] [PubMed]
Shibata S, Murota Y, Nishimoto Y, Yoshimura M, Nagai T, Okano H, Siomi MC. Immuno-Electron Microscopy and Electron Microscopic In Situ Hybridization for Visualizing piRNA Biogenesis Bodies in Drosophila Ovaries. Methods Mol Biol. 2015;1328:163-78. doi: 10.1007/978-1-4939-2851-4_12. [PubMed]
Masuda H, Maruyama T, Gargett CE, Miyazaki K, Matsuzaki Y, Okano H, Tanaka M. Endometrial Side Population Cells: Potential Adult Stem/Progenitor Cells in Endometrium. Biol Reprod. 2015 Aug 26. pii: biolreprod.115.131490. [Epub ahead of print] [PubMed]
Sugai K, Nishimura S, Kato-Negishi M, Onoe H, Iwanaga S, Toyama Y, Matsumoto M, Takeuchi S, Okano H, Nakamura M. Neural stem/progenitor cell-laden microfibers promote transplant survival in a mouse transected spinal cord injury model. J Neurosci Res. 2015 Aug 24. doi: 10.1002/jnr.23636. [Epub ahead of print] [PubMed]
Tsuyama J, Bunt J, Richards LJ, Iwanari H, Mochizuki Y, Hamakubo T, Shimazaki T, Okano H. MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells. Stem Cell Reports. 2015 Jul 22. pii: S2213-6711(15)00187-3. doi: 10.1016/j.stemcr.2015.06.006. [Epub ahead of print] [PubMed]
Shiratori-Hayashi M, Koga K, Tozaki-Saitoh H, Kohro Y, Toyonaga H, Yamaguchi C, Hasegawa A, Nakahara T, Hachisuka J, Akira S, Okano H, Furue M, Inoue K, Tsuda M. STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch. Nat Med. 2015 Jul 20. doi: 10.1038/nm.3912. [Epub ahead of print][PubMed]
Yokota K, Kobayakawa K, Kubota K, Miyawaki A, Okano H, Ohkawa Y, Iwamoto Y, Okada S. Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury. Stem Cell Reports. 2015 Jul 14. pii: S2213-6711(15)00185-X. doi: 10.1016/j.stemcr.2015.06.004. [Epub ahead of print] [PubMed]
Ono M, Kajitani T, Uchida H, Arase T, Oda H, Uchida S, Ota K, Nagashima T, Masuda H, Miyazaki K, Asada H, Hida N, Mabuchi Y, Morikawa S, Ito M, Bulun SE, Okano H, Matsuzaki Y, Yoshimura Y, Maruyama T. CD34 and CD49f Double-Positive and Lineage Marker-Negative Cells Isolated from Human Myometrium Exhibit Stem Cell-Like Properties Involved in Pregnancy-Induced Uterine Remodeling. Biol Reprod. 2015 Jun 24. pii: biolreprod.114.127126. [Epub ahead of print][PubMed]
Kondo T, Yoshihara Y, Yoshino-Saito K, Sekiguchi T, Kosugi A, Miyazaki Y, Nishimura Y, Okano HJ, Nakamura M, Okano H, Isa T, Ushiba J. Histological and electrophysiological analysis of the corticospinal pathway to forelimb motoneurons in common marmosets. Neurosci Res. 2015 Jun 17. pii: S0168-0102(15)00136-4. doi: 10.1016/j.neures.2015.05.001. [Epub ahead of print] [PubMed]
Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H. I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway. Hum Mol Genet. 2015 Jun 8. pii: ddv212. [Epub ahead of print] [PubMed]
Mabuchi Y, Okano H. Human somatic stem cell-based therapy for cartilage regeneration. Ann Transl Med. 2015 May;3(Suppl 1):S17. doi: 10.3978/j.issn.2305-5839.2015.02.35. [PubMed]
Iwai H, Shimada H, Nishimura S, Kobayashi Y, Itakura G, Hori K, Hikishima K, Ebise H, Negishi N, Shibata S, Habu S, Toyama Y, Nakamura M, Okano H. Allogeneic Neural Stem/Progenitor Cells Derived From Embryonic Stem Cells Promote Functional Recovery After Transplantation Into Injured Spinal Cord of Nonhuman Primates. Stem Cells Transl Med. 2015 May 27. pii: sctm.2014-0215. [Epub ahead of print] [PubMed]
Ishii K, Suzuki N, Mabuchi Y, Ito N, Kikura N, Fukada SI, Okano H, Takeda S, Akazawa C. Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation during Muscle Regeneration. Stem Cells. 2015 May 26. doi: 10.1002/stem.2058. [Epub ahead of print] [PubMed]
Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano H. Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage. Mol Brain. 2015 May 27;8(1):31. doi: 10.1186/s13041-015-0121-2. [PubMed]
Hikishima K, Ando K, Komaki Y, Kawai K, Yano R, Inoue T, Itoh T, Yamada M, Momoshima S, Okano HJ, Okano H. Voxel-based morphometry of the marmoset brain: In vivo detection of volume loss in the substantia nigra of the MPTP-treated Parkinson’s disease model. Neuroscience. 2015 May 23. pii: S0306-4522(15)00483-2. doi: 10.1016/j.neuroscience.2015.05.041. [Epub ahead of print] [PubMed]
Belmonte JC, Callaway EM, Churchland P, Caddick SJ, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J1, Zhang F. Brains, Genes, and Primates. Neuron. 2015 May 6;86(3):617-631. doi: 10.1016 [PubMed]
Yamamoto-Hino M, Muraoka M, Kondo S, Ueda R, Okano H, Goto S. Dynamic regulation of innate immune responses in Drosophila by Senju-mediated glycosylation. Proc Natl Acad Sci U S A. 2015 Apr 21. [Epub ahead of print][PubMed]
Okano H, Miyawaki A, Kasai K. Brain/MINDS: brain-mapping project in Japan. Philos Trans R Soc Lond B Biol Sci. 2015 May 19;370(1668). pii: 20140310. [PubMed]
Tsuboi D, Kuroda K, Tanaka M, Namba T, Iizuka Y, Taya S, Shinoda T, Hikita T, Muraoka S, Iizuka M, Nimura A, Mizoguchi A, Shiina N, Sokabe M, Okano H, Mikoshiba K, Kaibuchi K. Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nat Neurosci. 2015 Mar 30. doi: 10.1038 [PubMed]
Takata N, Yoshida K, Komaki Y, Xu M, Sakai Y, Hikishima K, Mimura M, Okano H, Tanaka KF. Optogenetic Activation of CA1 Pyramidal Neurons at the Dorsal and Ventral Hippocampus Evokes Distinct Brain-Wide Responses Revealed by Mouse fMRI. PLoS One. 2015 Mar 20;10(3):e0121417. doi: 10.1371 [PubMed]
Tokuno H, Watson C, Roberts A, Sasaki E, Okano H. Marmoset Neuroscience. Neurosci Res. 2015 Mar 12. pii: S0168-0102(15)00072-3. doi: 10.1016 [Epub ahead of print] [PubMed]
Kano SI, Yuan M, Cardarelli RA, Maegawa G, Horiuchi Y, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, Kato TA, Sedlak TW, Lee Y, Rapoport JL, Hirose S, Okano H, Valle D, O’Donnell P, Sawa A, Kai M. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Curr Mol Med. 2015 Mar 2. [Epub ahead of print] [PubMed]
Itakura G, Kobayashi Y, Nishimura S, Iwai H, Takano M, Iwanami A, Toyama Y, Okano H, Nakamura M. Controlling Immune Rejection Is a Fail-Safe System against Potential Tumorigenicity after Human iPSC-Derived Neural Stem Cell Transplantation. PLoS One. 2015 Feb 23;10(2):e0116413. doi: 10.1371 [PubMed]
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H. Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition. Stem Cell Reports. 2015 Mar 10;4(3):360-73. doi: 10.1016[PubMed]
Yamada I, Miyasaka N, Hikishima K, Tokairin Y, Kawano T, Ito E, Kobayashi D, Eishi Y, Okano H. Ultra-high-resolution MR imaging of esophageal carcinoma at ultra-high field strength (7.0 T) ex vivo: Correlation with histopathologic findings. Magn Reson Imaging. 2015 Jan 30. pii: S0730-725X(15)00039-9. doi: 10.1016/j.mri.2014.11.005. [Epub ahead of print] [PubMed]
Yu-Ching Lin Z, Hirano T, Shibata S, Seki NM, Kitajima R, Sedohara A, Siomi MC, Sasaki E, Siomi H, Imamura M, Okano H. Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development. Dev Biol. 2015 Apr 1;400(1):43-58. doi: 10.1016 [PubMed]
Hikishima K, Ando K, Yano R, Kawai K, Komaki Y, Inoue T, Itoh T, Yamada M, Momoshima S, Okano HJ, Okano H. Parkinson Disease: Diffusion MR Imaging to Detect Nigrostriatal Pathway Loss in a Marmoset Model Treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Radiology. 2015 Jan 15:140601. [Epub ahead of print] [PubMed]
Yamada I, Miyasaka N, Hikishima K, Kato K, Kojima K, Kawano T, Ito E, Kobayashi D, Eishi Y, Okano H. Gastric Carcinoma: Ex Vivo MR Imaging at 7.0 T-Correlation with Histopathologic Findings. Radiology. 2015 Jun;275(3):841-8. doi: 10.1148/radiol.14141878. Epub 2015 Jan 14. [PubMed]
Fujioka M, Okano H, Edge AS. Manipulating cell fate in the cochlea: a feasible therapy for hearing loss. Trends Neurosci. 2015 Mar;38(3):139-144. doi: 10.1016 [PubMed]
