2006年

Jomphe C., Lemelin PL., Okano H., Kobayashi K., Trudeau LE.: Bidirectionalregulation of dopamine D2 and neurotensin NTS1 receptors indopamineneurons.
Eur. J. Neurosci. 24: 2789-2800, 2006 [PubMed]

Kaneko N., Okano H., Sawamoto K.: The role of cholinergic system in regulating survival of new neurons in the adult mouse dentate gyrus and olfactory bulb.
Genes to Cells 11: 1145-1159, 2006. [PubMed]

Yamashita T., Deguchi K., Sawamoto K., Okano H., Kamiya T., Abe K.:Neuroprotection and neurosupplementation in ischaemic brain.
Biochem Soc Trans. 34 (Pt 6):1310-1312, 2006. [PubMed]

Terakawa M., Sato S., Ashida H., Okano H., Obara M.: Integrity of plasmid deoxynucleic acid after appication of laser-induced stress waves used for gene transfection. Jpn.
J. Appl. Phys. 45: pp. L768-L769, 2006. [PubMed]

Kaneko S., Iwanami A., Nakamura M., Kishino A., Kikuchi K., Shibata S., Okano HJ., Ikegami T., Moriya A., Konishi O., Nakayama C., Kumagai K., Kimura T., Sato Y., Goshima Y., Taniguchi M., Ito M., He Z., Toyama Y., Okano H.:  A selective Sema3A-inhibitor enhances regenerative responses and functional recovery of the injured spinal cord.
Nat. Med. 12: 1380-1389, 2006. [PubMed]

Okano H.: Adult neural stem cells and central nervoussystem repair.
Ernst Schering Res Found Workshop. 60: 215-228, 2006. [PubMed]

Yoshida S., Shimmura S., Nagoshi N., Matzuzaki Y., Fukuda K., Okano H., Tsubota K.: Isolation of multipotent neural crest-derived stem cells from the adult cornea.
Stem Cells, 24: 2714-2722, 2006. [PubMed]

Yamashima T., Popivanova BK., Guo J., Tonchev AB., Kotani S., Wakayama T., Iseki S., Sawamoto K., Okano H., Fujii C., Mukaida N.: Implication of ‘Down syndrome cell adhesion molecule’ in adult neurogensis of monkey hippocampus after ischemia.
Hippocampus, 16: 924-935, 2006. [PubMed]

Ishii K., Nakamura M., Dai HN., Finn TP., Okano H., Toyama Y., Bregman BS.: Neutralization of Ciliary Neurotrophic Factor reduces astrocyte production from transplanted neural stem cells and promotes regeneration of corticospinal tract fibers in spinal cord injury.
J. Neurosci Res, 84: 1669-1681, 2006. [PubMed]

Mori H., Ninomiya K., Kino-oka M., Shofuda T., Islam MO., Yamasaki M., Okano H., Taya M, Kanemura Y
J. Neurosci Res.,
84:1682-1691, 2006. [PubMed]

Kurihara T., Ozawa Y., Shinoda K., Nagai N., Inoue M., Oike Y., Tsubota K., Ishida S., Okano H.: Role of the angiotensin II type 1 receptor (AT1R) blocker, telmisartan, in neuroprotection against retinal inflammation.
IOVS 47: 545-5552, 2006. [PubMed]

Arata Y., Kouike H., Zhang Y., Herman M., Okano H., Sawa H.: Wnt signaling and a Hox protein cooperatively regulate PSA-3/MEIS to determine daughter cell fate after asymmetric cell division in C. elegans. Dev. Cell 11: 105-115, 2006. [PubMed]

Okada S., Ishii K., Miyao T,. Shimzakai T., Katoh H., Yamane J., Yoshimura A., Iwamoto Y., Nakamura M., Toyama Y., Okano H.: Conditional ablation of STAT3/SOCS3 discloses a dual role for reactive astrocytes after spinal cord injury. Nat. Med. 12: 829-834, 2006. [PubMed]

Chan C., Moore BE., Cotman CW., Okano H., Tavares R., Hovanesian V., Pinar H., Johanson CE., Svendsen CN., Stopa EG.: Musashi1 antigen expression in human fetal germinal matrix development.
Exp. Neurol. 201: 515-518, 2006. [PubMed]

Ninomiya M., Yamashita T., Araki N., Okano H., Sawamoto K.: Enhanced neurogenesis in the ischemic striatum following EGF-induced expansion of transit-amplifying precursors in the subventricular zone.
Neurosci. Lett. 403: 63-67, 2006. [PubMed]

Yamashita T., Ninomiya M., Acosta PH., García-Verdugo JM., Takehiko Sunabori T., Sakaguchi M., Adachi K., Kojima T., Hirota Y., Kawase T., Araki, N., Abe K., Okano H., Sawamoto K.: Subventricular-zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum.
J. Neurosci. 26: 6627-6636, 2006. [PubMed]

Sakaguchi M., Shingo T., Shimazaki T., Okano HJ., Shiwa M., Ishibashi S., Oguro H., Ninomiya M., Kadoya T., Horie H., Shibuya A., Mizusawa H., Poirier F., Nakauchi H., Sawamoto K., Okano H.: A carbohydrate binding protein, Galectin-1, promotes proliferation of adult neural stem cells.
Proc. Natl. Acad. Sci. USA 103: 7112-7117, 2006. [PubMed]

Hara T., Nakamura K., Nakahara Y., Migishima R,. Yokoyama M., Okano H., Mizushima N.: Suppression of autophagy in neural cells causes a neurodegenerative disease.
Nature 441: 885-889, 2006. [PubMed]

Miyagi S., Nishimoto M., Saito T., Ninomiya M., Sawamoto K., Okano H., Muramatsu M., Oguro H., Iwama A., Okuda A.: The Sox2 regulatory region 2 functions as a neural stem cell specific enhancer in the telencephalon. J. Biol. Chem. 281: 13374-13381, 2006. [PubMed]

Arttamangkul S., Torrecilla M., Kobayashi K., Okano H., Williams JT.: Separation of Mu opioid receptor desensitization and internalization.
J. Neurosci, 26: 4118-4125, 2006. [PubMed]

Rawal N., Castelo-Branco G., Sousa KM., Kobayashi K., Okano H., Arenas E.: Spatial and temporal expression dynamics of Wnt signaling components in the developing midbrain.
Exp. Cell Res. 312: 1626-1636, 2006. [PubMed]

Murata J., Tokunaga A., Okano H., Kubo T.: Notch1 activation demonstrated in situ, during mouse cochlear development.
J. Comp. Neurol. 497: 502-518, 2006. [PubMed]

Tonchev AB., Yamashima T., Sawamoto K., Okano H.: Transcription factor protein expression patterns by neural or neuronal progenitor cells of adult monkey subventricular zone.
Neuroscience 139: 1355-1367, 2006. [PubMed]

Okano H.: Thoughts on the biomedical sciences in Japan and Australia.
Inflammation and Regeneration. 26: 16-17, 2006.

Sawamoto K., Wichterle H., Gonzalez-Perez O., Cholfin JA., Yamada M., Spassky N., Murcia NS., Garcia-Verdugo JM., Martin O., Rubenstein JL., Tessier-Lavigne M., Okano H., Alvarez-Buylla, A.: New neurons follow the flow of cerebrospinal fluid in the adult brain.
Science 311: 629-631, 2006. [PubMed]

Matsumoto A., Okada Y., Nakamichi M., Nakamura M., Aoki M., Sobue G., Itoyama Y. and Okano H.: Disease progression of SOD1 (G93A) ALS model rats.
J. Neurosci. Res. 83: 119-133, 2006. [PubMed]

Takenaga M., Ohta Y., Tokura Y., Hamaguchi A., Nakamura M., Okano H., Igarashi R.: Lecithinized superoxide dismutase (PC-SOD) improved spinal cord injury-induced motor dysfunction through suppression of oxidative stress and enhancement of neurotrophic factor production.
J. Control Release. 110: 283-289, 2006. [PubMed]

Nagata H., Akiba Y., Suzuki H., Okano H., Hibi T.: Expression of Musashi-1 in the rat stomach and changes during mucosal injury and reconstitution. FEBS Lett. 580: 27-33, 2006. [PubMed]

Kanai R., Tomita H., Shinoda A., Takahashi M., Goldman SA., Okano H., Kawase T., Yazaki T.: Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of 34.5-mediated virulence. Gene Therapy 13: 106-116, 2006. [PubMed]

Fujioka M., Kanzaki S., Okano HJ., Masuda M., Ogawa K., Okano H.: Proinflammatory cytokines expression in noise-induced damaged cochlea. J. Neurosci. Res. 83: 575-583, 2006. [PubMed]

Kawada H., Takizawa S., Takanashi T., Morita Y., Fujita J., Fukuda K., Takagi S., Okano H., Ando K., Hotta T.: Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem cells and transition of bone marrow-derived neuronal cells.
Circulation 113: 701-710, 2006. [PubMed]

Nishimura T., Yamaguchi T., Tokunaga A., Hara A., Hamaguchi T., Kato K., Iwamatsu A., Okano H., Kaibuchi K.: Role of Numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
Mol. Biol. Cell 17: 1273-1285, 2006. [PubMed]

Toriya M., Tokunaga A., Sawamoto K., Nakao K., Okano H.: Distinct functions of human Numb isoforms revealed by misexpression in neural precursor cells in Drosophila larval brain.
Dev. Neurosci. 28: 142-155, 2006. [PubMed]

Sugiyama-Nakagiri Y., Akiyama M., Shibata S., Okano H., Shimizu H.: Expression of RNA-binding protein Musashi in hair follicle development and hair cycle progression.
Am. J. Pathology 168: 80-92, 2006. [PubMed]

Fukuhara Y., Li X-K, Kitazawa Y., Inagaki M., Matsuoka K., Kosuga M., Kosaki R., Shimazaki T., Endo H., Umezawa A., Okano H., Takahashi T., Okuyama T.: Histopathological and behavioral improvement of murine Mucopolysaccharidosis type VII by intra-cerebral transplantation of neural stem cells.
Molecular Therapy 13: 548-555, 2006. [PubMed]

Okano H., Nakamura M., Toyama Y.: Stem cell therapies for injured spinal cord. Inflammation and Regeneration 26: 18-28, 2006.

Okano H., Kohyama J., Ohba H., Sakaguchi M., Tokunaga A., Shimazaki T., Okano HJ.: Neural stem cells: Isolation and self-renewal. In Tissue Stem Cells;
Biology & Applications. (Edited by Potten , Wilson, Clarke, Renehan, Marcel Dekker), Taylor & Francis Group, LLC, New York, pp. 55-70, 2006.

Okano H.: Transplantation of neural stem cells for spinal cord regeneration. In
Encyclopedic References of Neuroscience (Edited by Binder D, Hirokawa N and Windhorst U) Springer-Verlag (Heidelberg, Germany), In Press, 2006.

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