2011年

Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H. Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex J. Neurosci. 2011 Nov 16;31(46):16872-83. [PubMed]

Kanda H, Igaki T, Okano H, Miura M. Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death Proc.Natl.Acad.Sci.USA 2011 Nov 22;108(47):18977-82 [PubMed]

 

Yasuda A, Tsuji O, Shibata S, Nori S, Takano M, Kobayashi Y, Takahashi Y, Fujiyoshi K, Hara CM, Miyawaki A, Okano HJ, Toyama Y, Nakamura M, Okano H. Significance of remyelination by neural stem/progenitor cells transplanted into the injured spinal cord Stem Cells 2011 Dec; 29(12):1983-94 [PubMed]

Yamane J, Ishibashi S, Sakaguchi M, Kuroiwa T, Kanemura Y, Nakamura M, Miyoshi H, Sawamoto K, Toyama Y, Mizusawa H, Okano H. Transplantation of human neural stem/progenitor cells overexpressing Galectin-1 improves functional recovery from focal brain ischemia in the Mongolian gerbil. Mol Brain 2011 Sep 27;4(1):35. [PubMed]

 

Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H. Grafted human induced pluripotent stem cell-derived neurospheres promotes motor functional recovery after spinal cord injury in mice. Proc.Natl.Acad.Sci.USA 2011 Oct 4;108(40):16825-30. [PubMed]

 

Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, Okano H. The dual origin of the peripheral olfactory system: placode and neural crest. Mol Brain. 2011 Sep23;4(1):34. [PubMed]

 

Sakaguchi M, Arruda-Carvalho M, Kang NH, Imaizumi Y, Poirier F, Okano H, Frankland PW. Impaired spatial and contextual memory formation in galectin-1 deficient mice. Mol. Brain 4(1):33, 2011 [PubMed]

 

Okano H. Strategic approaches to regeneration of a damaged central nervous system. Cornea. 2011 Oct;30 Suppl 1:S15-8. [PubMed]

 

Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura KI, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M. Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest. 2011 Sep12. pii: 57301. doi: 10.1172/JCI57301. [Epub ahead of print] [PubMed]

 

Tsuji O, Miura K, Fujiyoshi K, Nakamura M, Okano H.: Neural stem cell therapy via iPS/ES cells. Neurotherapeutics 2011 Sep 10. [Epub ahead of print] [PubMed]

 

Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N. Modeling familial Alzheimer’s disease with induced pluripotent stem cells. Hum Mol Genet. 2011 Dec 1;20(23):4530-9. [PubMed]

 

Renault-Mihara F, Katoh H, Ikegami T, Iwanami A, Mukaino M, Yasuda A, Nori S, Mabuchi Y, Tada H, Shibata S, Saito K, Matsushita M, Kaibuchi K, Okada S, Toyama Y, Nakamura M, Okano H.: Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition. EMBO Mol Med. 2011 Nov;3(11):682-96. [PubMed]

 

Takagi T, Ishii K, Shibata S, Yasuda A, Sato M, Nagoshi N, Saito H, Okano HJ, Toyama Y,Okano H: Schwann-spheres derived from injured peripheral nerves in adult mice–their in vitro characterization and therapeutic potential. PLoS ONE 6(6):e21497, 2011 [PubMed]

Nakamura M,Tsuji O, Bregman BS, Toyama Y,Okano H: Mimicking the neurotrophic factor profile of the embryonic spinal cord inhibits the differentiation of spinal progenitor cells into astrocytes and promotes their differentiation into neurons and oligodendrocytes. PLoS ONE 6(6):e20717, 2011 [PubMed]

 

Masanao T, Ohta S, Ohashi Y, Fukaya R, Yoshida K, Kawase T, Saya H, Thirant C, Chneiweiss H, Matsuzaki Y, Okano H, Kawakami Y and Toda M.: Functional analysis of HOXD9 in human gliomas and  glioma cancer stem cells. Molecular Cancer 10(1):60, 2011 [PubMed]

 

Fujioka M, Tokano H, Fujioka-Shiina K, Okano H, Edge A.S. : Cre/lox mediated in vivomosaic cell ablation to generate novel models for early stages of degenerative disease and tissue repair. J. Clin. Invest. 121(6):2462-2469, 2011  [PubMed]

 

Kubota Y, Hirashima M, Takubo K, Nagoshi N, Kishi K, Murakami M, Shibuya M, Takakura N, Okano H, Suda T. :Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J. Exp. Med 208(5): 949-960, 2011 [PubMed]

Kawase S, Imai T, Miyauchi-Hara C, Yaguchi K, Nishimoto Y, Fukami SI, Matsuzaki Y, Miyawaki A, Itohara S, Okano H. : Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/protenitor cells. Mol Brain (4):14, 2011 [PubMed]

Ishizuka K, Kamiya A, Oh EC, Kanki H, Sehadri S, Robinson J, Murdoch H, Dunlop AJ, Kubo KI, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, Houslay MD, Katsanis N, Sawa A. :DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature 2011 May 5;473(7345):92-6. [PubMed]

Cucchiaroni ML, Freestone PS, Berretta N, Viscomi MT, Bisicchia E, Okano H, Molinari M, Bernardi G, Lipski J, Mercuri NB, Guatteo E: Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures – evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. Eur J Neurosci. 2011 Mar 31.[PubMed]

Niibe K, Kawamura Y, Araki D, Morikawa S, Miura K, Suzuki S, Shimmura S, Sunabori T, Mabuchi Y, Nagai Y, Nakagawa T, Okano H, Matsuzaki Y: Purified mesenchymal stem cells are an efficient source for iPS cell induction. PLoS One, 6(1):e16182, 2011.[PubMed]

Kawahara H, Okada Y, Imai T, Iwanami A, Mischell PS, Okano H: An RNA-binding protein Musashi1 co-acts on Lin28-mediated Let-7 family miRNA biogenesis in early neural differentiation. J. Biol.Chem., 2011 Mar 4. [Epub ahead of print] [PubMed]

Nagoshi N, Shibata S, Nakamura M, Mabuchi Y, Matsuzaki Y, Toyama Y, and Okano H: Schwann Cell Plasticity After Spinal Cord Injury Shown by Neural Crest Lineage Tracing. Glia 59(5): 771-84, 2011 [PubMed]

Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI: Fbxw7-dependent degradation of Notch is required for control of stemness and neuronal-glial differentiation in neural stem cells. J Biol Chem. 2011 Feb 24.[Epub ahead of print] [PubMed]

Doi Y, Shinzawa N, Fukumoto S, Okano H, Kanuka H: Calcium signal regulates temperature-dependent transformation of sporozoites in malaria parasite development. Exp Parasitol. 2011 Feb 15. [Epub ahead of print] [PubMed]

Hosoya M, Fujioka M, Matsuda S, Ohba H, Shibata S, Nakagawa F, Wakabayashi K, Saga Y, Ogawa K, Okano HJ, Okano H: Expression and the function of Sox21 during mouse cochlea development. Neurochem Res, 2011 Feb 3. [Epub ahead of print] [PubMed]

Cheng HC, Kim SR, Oo TF, Kareva T, Yarygina O, Rzhetskaya M, Wang C, During M, Talloczy Z, Tanaka K, Komatsu M, Kobayashi K, Okano H, Kholodilov N, Burke RE: Schwann AKT suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy. J. Neurosci. 31(6):2125-35, 2011 [PubMed]

Imaizumi Y, Sakaguchi M, Morishita T, Ito M, Shingo T, Hirabayashi J, Poirier F, Sawamoto K, Okano H: Galectin-1 inhibits the proliferation of neural precursor cells in the adult dentate gyrus. Molecular Brain, 4(1):7, 2011 [PubMed]

Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohayama M, Amagai M, Matsuzaki Y, Yamamanaka S, Okano H, Kawakami Y: Generation of human melanocytes from induced pluripotent stem cells. PLoS ONE, 6(1):e16182, 2011 [PubMed]

Niibe K, Morikawa S, Mabuchi Y, Araki D, Nakagawa T, Okano H, Matsuzaki Y: Mesp1+ early paraxial mesodermal cells supply initial bone marrow mesenchymal stem cells capable of differentiating into neural crest lineage cells. Inflammation and Regeneration, 31(1): 116-124, 2011 [PDF]

Miura K, Tsuji O, Nakamura M, Okano H: Toward using iPS cells to treat spinal cord injury: Their safety and therapeutic efficacy. Inflammation and Regeneration, 31(1):2-10, 2011 [PDF]

Okano H: Welcome to New Era of Inflammation and Regeneration. Inflammation and Regeneration, 31(1): 1, 2011 [PDF]

Sawamoto K, Hirota Y, Alfaro-Cervello C, Soriano-Navarro M, He X, Hayakawa-Yano Y, Yamada M, Hikishima K, Tabata H, Iwanami A, Nakajima K, Toyama Y, Itoh T, Alvarez-Buylla A, Garcia-Verdugo JM, and Okano H: Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain. J. Comp. Neurol. 519(4):690-713, 2011 [PubMed]

Tamura Y, Matsumura K, Sano M, Tabata H, Kimura K, Ieda M, Arai T, Ohno Y, Kanazawa H, Yuasa S, Kaneda R, Makino S, Nakajima K, Okano H, Fukuda K: Neural Crest-Derived Stem Cells Migrate and Differentiate Into Cardiomyocytes After Myocardial Infarction. Arterioscler Thromb Vasc Biol., 2011 Jan 6. [Epub ahead of print] [PubMed]

Orihara-Ono M, Toriya M, Nakao K, Okano H: Downregulation of Notch mediates the seamless transition of individual Drosophila neuroepithelial progenitors into optic medullar neuroblasts during prolonged G1. Dev. Biol. 54(4):2741-2749, 2011 [PubMed]

Ozawa Y, Kurihara T, Tsubota K, Okano H: Regulation of posttranscriptional modification as a possible therapeutic approach for retinal neuroprotection. J Ophthalmol. 2011;2011:506137 [PubMed]

Igaki T, Kanda H, Okano H, Xu T, Miura M: Eiger and Wengen: The Drosophila Orthologs of TNF/TNFR. Adv Exp Med Biol. 691:45-50, 2011 [PubMed]

Shinozaki M, Takahashi Y, Mukaino M, Saito N, Toyama Y, Okano H, Nakamura M: Novel Concept of Motor Functional Analysis for Spinal Cord Injury in Adult Mice. J. Biomed Biotech, 2011: Article ID 157458, 7 page, 2011 [PubMed]

Shiozawa S, Kawai K, Okada Y, Tomioka I, Maeda T, Kanda A, Suemizu H, Shinohara H, Okano HJ, Sotomaru Y, Sasaki E, Okano H: Gene targeting and subsequent site-specific transgenesis in b-actin (ACTB) locus of the common marmoset embryonic stem cells. Stem Cells Dev., 2010 Dec 2. [Epub ahead of print] [PubMed]

Hikishima K, Quallo MM, Komaki Y, Yamada M, Kawai K, Momoshima S, Okano HJ, Sasaki E, Tamaoki N, Lemon RN, Iriki A, Okano H: Population-averaged Standard Template Brain Atlas for the Common Marmoset (Callithrix jacchus). NeuroImage 54(4):2741-2749, 2011 [PubMed]

Takahashi Y, Tsuji O, Kumagai G, Hara C, Miyawaki A, Toyama Y, Okano H, Nakamura M: Comparative study of different administrations of neural stem/progenitor cells for spinal cord injury in mice. mice. Cell Transplant. 2010 Nov 5. [Epub ahead of print] (H. Okano is the corresponding author in this paper) [PubMed]

Hamanoue M and Okano H: Cell surface N-glycans mediated isolation of mouse neural stem cells. J Cell Physiol. 2010 Oct 13. [Epub ahead of print] [PubMed]

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